medications with narrow therapeutic window

Maintain plasma drug concentrations withinĪ predetermined range in order to optimize

Therapeutic concentrations with minimum toxicĬoncentration. That produces a therapeutic response withoutĬausing any adverse effect. Range has usually described the range of doses Maintaining blood drug concentrations within a Provide adequate and safe drug therapy through Optimization of the dosage regimen which can The drug concentrations in patient’s blood e.g. Pharmacy which is specific to a measure of Therapeutic drug monitoring (TDM), clinical service, HPLC Introductionīranch of clinical pharmacology and clinical This review summarizes the key concept of therapeutic drug monitoring, its historical background, pharmacokinetic principles, the role of clinician and its future scope of TDM in clinical practice. The main purpose of TDM is to use appropriate blood drug concentrations that possess a narrow therapeutic spectrum in order to optimize the clinical results. The clinician manages the cases of a drug overdose and decides how to recoup drug toxicity with limited pharmaceutical requirements and figure out patient consent along with treatment. Clinicians approach the laboratory to monitor drug concentration to minimize toxicity and enhance therapeutic responses. Therapeutic drug monitoring is a clinical service in which to measuring different drugs in different time periods to manage a desired concentration of drugs in the patient’s blood. International University, Malaysia Corresponding Author: Mohammad Asif Rabia Basharat 2 Nauman Anwer Rana 1 and Saeed Akhtar khan

Medications with narrow therapeutic window